Hyeon, Changbong
Professor
Theoretical and Computational Biophysics
Changbong Hyeon works mostly on theoretical and computational studies of biological systems. The emergence of life from individual physicochemical processes of cellular constituents is a major outstanding question in biophysics. The research interests of this group lie in the dynamics of DNA, RNA, and proteins at the single molecule level, as well as in the interactions among these molecules in giant macromolecular complexes such as chromosomes. Studies towards understanding how the interactions between self-organized biopolymers contribute to the emergence of life at nonequilibrium in which energy is continuously injected in and dissipated out of the system are a long-term research goal. Major contributions have recently been made in areas such as: (i) the physical principles underlying molecular motors, (ii) the origin of heterogeneity in biomolecular processes, and (iii) nonequilibrium thermodynamics in living systems.
- 1991-1995, B.S., Chemistry, Seoul National University
- 1995-1997, M.S., Chemistry, Seoul National University
- 2000-2005 Ph.D., Chemical Physics, University of Maryland, College Park
- 2006-2008 Postdoctoral Research Associate, Center for Theoretical Biological Physics, UC San Diego
- 2008-2009 Assistant Professor, Chemistry, Chung-Ang University, Seoul
- 2010-present Professor of Computational Sciences, Korea Institute for Advanced Study, Seoul
Publications at KIAS
-
Fundamental trade-off between the speed of light and the Fano factor of photon current in three-level lambda systems
JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL, 2023 -
Polymer Physics-Based Classification of Neurons
NEUROINFORMATICS, 2023 -
Solvent Quality Dependent Osmotic Pressure of Polymer Solutions in Two Dimensions
JOURNAL OF PHYSICAL CHEMISTRY B, 2022 -
Dissecting the cosegregation probability from genome architecture mapping
BIOPHYSICAL JOURNAL, 2022 -
Olfactory responses of Drosophila are encoded in the organization of projection neurons
ELIFE, 2022 -
Location of the TEMPO moiety of TEMPO-PC in phosphatidylcholine bilayers is membrane phase dependent
BIOPHYSICAL JOURNAL, 2022 -
Extracting multi-way chromatin contacts from Hi-C data
PLOS COMPUTATIONAL BIOLOGY, 2021 -
Origin of loose bound of the thermodynamic uncertainty relation in a dissipative two-level quantum system
PHYSICAL REVIEW E, 2021 -
Cost-precision trade-off relation determines the optimal morphogen gradient for accurate biological pattern formation
ELIFE, 2021 -
Thermodynamic Optimality of Glycolytic Oscillations
JOURNAL OF PHYSICAL CHEMISTRY B, 2021 -
Polymer brush-induced depletion interactions and clustering of membrane proteins
JOURNAL OF CHEMICAL PHYSICS, 2021 -
Extreme parsimony in ATP consumption by 20S complexes in the global disassembly of single SNARE complexes
NATURE COMMUNICATIONS, 2021 -
Thermodynamic uncertainty relation to assess biological processes
JOURNAL OF CHEMICAL PHYSICS, 2021 -
A unified framework for inferring the multi-scale organization of chromatin domains from Hi-C
PLOS COMPUTATIONAL BIOLOGY, 2021 -
Revisiting the organization of Polycomb-repressed domains: 3D chromatin models from Hi-C compared with super-resolution imaging
NUCLEIC ACIDS RESEARCH, 2020 -
Thermodynamic cost of synchronizing a population of beating cilia
JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT, 2020 -
Water-mediated biomolecular dynamics and allostery
JOURNAL OF CHEMICAL PHYSICS, 2020 -
Thermodynamic Cost, Speed, Fluctuations, and Error Reduction of Biological Copy Machines
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2020 -
Near-Theta Polymers in a Cylindrical Space
MACROMOLECULES, 2020 -
Theoretical perspectives on biological machines
REVIEWS OF MODERN PHYSICS, 2020 -
Iterative annealing mechanism explains the functions of the GroEL and RNA chaperones
PROTEIN SCIENCE, 2020 -
Increased Confinement and Polydispersity of STIM1 and Orai1 after Ca2+ Store Depletion
BIOPHYSICAL JOURNAL, 2020 -
Heterogeneous Loop Model to Infer 3D Chromosome Structures from Hi-C
BIOPHYSICAL JOURNAL, 2019 -
Compressing Theta-Chain in Slit Geometry
NANO LETTERS, 2019 -
Symmetry, Rigidity, and Allosteric Signaling: From Monomeric Proteins to Molecular Machines
CHEMICAL REVIEWS, 2019 -
Chain organization of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci
PLOS COMPUTATIONAL BIOLOGY, 2018 -
From octopus to dendrite-Semiflexible polyelectrolyte brush condensates in trivalent counterion solution
JOURNAL OF CHEMICAL PHYSICS, 2018 -
Dynamic coordination of two-metal-ions orchestrates lambda-exonuclease catalysis
NATURE COMMUNICATIONS, 2018 -
Thermodynamic uncertainty relation of interacting oscillators in synchrony
PHYSICAL REVIEW E, 2018 -
Interphase human chromosome exhibits out of equilibrium glassy dynamics
NATURE COMMUNICATIONS, 2018 -
Oligomer Formation Propensities of Dimeric Bundle Peptides Correlate with Cell Penetration Abilities
ACS CENTRAL SCIENCE, 2018 -
Signalling networks and dynamics of allosteric transitions in bacterial chaperonin GroEL: implications for iterative annealing of misfolded proteins
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2018 -
Time- evolving genetic networks reveal a NAC troika that negatively regulates leaf senescence in Arabidopsis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018 -
Implications for human odor sensing revealed from the statistics of odorant-receptor interactions
PLOS COMPUTATIONAL BIOLOGY, 2018 -
Energetic Costs, Precision, and Transport Efficiency of Molecular Motors
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2018 -
Molecular chaperones maximize the native state yield on biological times by driving substrates out of equilibrium
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017 -
Heterogeneity in kinesin function
TRAFFIC, 2017 -
Ultrasensitivity of Water Exchange Kinetics to the Size of Metal Ion
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017 -
Physical insight into the thermodynamic uncertainty relation using Brownian motion in tilted periodic potentials
PHYSICAL REVIEW E, 2017 -
Ripping RNA by Force Using Gaussian Network Models
JOURNAL OF PHYSICAL CHEMISTRY B, 2017 -
Heterogeneous Morphology and Dynamics of Polyelectrolyte Brush Condensates in Trivalent Counterion Solution
MACROMOLECULES, 2017 -
Kinetic Model for the Activation of Mammalian Olfactory Receptor
JOURNAL OF PHYSICAL CHEMISTRY B, 2017 -
Quantifying the Heat Dissipation from a Molecular Motor's Transport Properties in Nonequilibrium Steady States
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2017 -
Decoding Single Molecule Time Traces with Dynamic Disorder
PLOS COMPUTATIONAL BIOLOGY, 2016 -
Effects of Dimethyl Sulfoxide on Surface Water near Phospholipid Bilayers
BIOPHYSICAL JOURNAL, 2016 -
Ultraslow Water-Mediated Transmembrane Interactions Regulate the Activation of A(2A) Adenosine Receptor
BIOPHYSICAL JOURNAL, 2016 -
How are molecular crowding and the spatial organization of a biopolymer interrelated
SOFT MATTER, 2016 -
Contact Statistics Highlight Distinct Organizing Principles of Proteins and RNA
BIOPHYSICAL JOURNAL, 2016 -
Directly measuring single-molecule heterogeneity using force spectroscopy
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016 -
Using Simulations and Kinetic Network Models to Reveal the Dynamics and Functions of Riboswitches
COMPUTATIONAL METHODS FOR UNDERSTANDING RIBOSWITCHES, Methods in Enzymology, 2015 -
Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover
SCIENCE, 2015 -
Deciphering Kinetic Information from Single-Molecule FRET Data That Show Slow Transitions
JOURNAL OF PHYSICAL CHEMISTRY B, 2015 -
Confinement-Induced Glassy Dynamics in a Model for Chromosome Organization
PHYSICAL REVIEW LETTERS, 2015 -
Unexpected Swelling of Stiff DNA in a Polydisperse Crowded Environment
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015 -
Effects of Macromolecular Crowding on the Collapse of Biopolymers
PHYSICAL REVIEW LETTERS, 2015 -
Communication over the Network of Binary Switches Regulates the Activation of A(2A) Adenosine Receptor
PLOS COMPUTATIONAL BIOLOGY, 2015 -
Programmed folding of DNA origami structures through single-molecule force control
NATURE COMMUNICATIONS, 2014 -
Development and Applications of Coarse-Grained Models for RNA
ISRAEL JOURNAL OF CHEMISTRY, 2014 -
Dynamical Transition and Heterogeneous Hydration Dynamics in RNA
JOURNAL OF PHYSICAL CHEMISTRY B, 2014 -
Sequence-dependent folding landscapes of adenine riboswitch aptamers
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2014 -
Destabilization of i-Motif by Submolar Concentrations of a Monovalent Cation
JOURNAL OF PHYSICAL CHEMISTRY B, 2014 -
Mapping the intramolecular signal transduction of G-protein coupled receptors
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2014 -
Evidence of Disorder in Biological Molecules from Single Molecule Pulling Experiments
PHYSICAL REVIEW LETTERS, 2014 -
Generalized iterative annealing model for the action of RNA chaperones
JOURNAL OF CHEMICAL PHYSICS, 2013 -
Urea-Induced Denaturation of PreQ(1)-Riboswitch
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013 -
Real-Time Observation of Multiple-Protein Complex Formation with Single-Molecule FRET
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013 -
Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism
NATURE COMMUNICATIONS, 2013 -
Real-time single-molecule co-immunoprecipitation analyses reveal cancer-specific Ras signalling dynamics
NATURE COMMUNICATIONS, 2013 -
RNA under Tension: Folding Landscapes, Kinetic Partitioning Mechanism, and Molecular Tensegrity
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2012 -
The Origin of Minus-end Directionality and Mechanochemistry of Ncd Motors
PLOS COMPUTATIONAL BIOLOGY, 2012 -
Hidden complexity in the isomerization dynamics of Holliday junctions
NATURE CHEMISTRY, 2012 -
Weak temporal signals can synchronize and accelerate the transition dynamics of biopolymers under tension
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012 -
Multiple barriers in forced rupture of protein complexes
JOURNAL OF CHEMICAL PHYSICS, 2012 -
Efficient Functional Delivery of siRNA using Mesoporous Silica Nanoparticles with Ultralarge Pores
SMALL, 2012 -
Force-induced Unbinding Dynamics in a Multidimensional Free Energy Landscape
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2012 -
Chain Length Determines the Folding Rates of RNA
BIOPHYSICAL JOURNAL, 2012 -
Link between Allosteric Signal Transduction and Functional Dynamics in a Multisubunit Enzyme: S-Adenosylhomocysteine Hydrolase
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011 -
A Structural Perspective on the Dynamics of Kinesin Motors
BIOPHYSICAL JOURNAL, 2011 -
Capturing the essence of folding and functions of biomolecules using coarse-grained models
NATURE COMMUNICATIONS, 2011 -
Compaction and Tensile Forces Determine the Accuracy of Folding Landscape Parameters from Single Molecule Pulling Experiments
PHYSICAL REVIEW LETTERS, 2011 -
Dynamic Ca2+-Dependent Stimulation of Vesicle Fusion by Membrane-Anchored Synaptotagmin 1
SCIENCE, 2010 -
Theoretical Perspectives on Protein Folding
ANNUAL REVIEW OF BIOPHYSICS, VOL 39, 2010
Publications(Career)
-
A unified framework for inferring the multi-scale organization of chromatin domains from Hi-C
PLOS Computational Biology 17 (3), e1008834 -
Revisiting the organization of Polycomb-repressed domains: 3D chromatin models from Hi-C compared with super-resolution imaging
Nucl. Acids Res. (2020) 48, 11486-11494 -
Thermodynamic cost of synchronizing a population of beating cilia
J. Stat. Mech. (2020) 074001 -
Water-mediated biomolecular dynamics and allostery
J. Chem. Phys. (2020) 152, 240901 -
Thermodynamic cost, speed, fluctuations, and error reduction of biological copy machines
J. Phys. Chem. Lett. (2020) 11, 3136-3143 -
Near-Θ polymers in a cylindrical space
Macromolecules (2020) 53, 2412-2419 -
Theoretical Perspectives on Biological Machines
Rev. Mod. Phys. (2020) 92, 025001 -
Increased Confinement and Polydispersity of STIM1 and Orai1 after Ca2+ Store Depletion
Biophys. J. (2020) 118, 70-84 -
Compressing Θ-chain in slit geometry
Nano Letters (2019) 19, 5667-5673 -
Heterogeneous loop model to infer 3D chromosome structures from Hi-C
Biophys. J. (2019) 117, 613-625 -
Symmetry, Rigidity, and Allosteric Signaling: From Monomeric Proteins to Molecular Machines
Chemical Reviews (2019) 119, 6788-6821 -
Chain organization of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci
PLOS Comp. Biol. (2018) 14, e1006175, 2018 -
Dynamic Coordination of Two-Metal-Ions Orchestrates λ-Exonuclease catalysis
Nature Communications (2018) 9:4404 -
Thermodynamic uncertainty relation of interacting oscillator in synchrony
Phys. Rev. E. (2018) 98, 032119 -
Interphase human chromosome exhibits out of equilibrium glassy dynamics
Nature Communications (2018) 9:3161 -
Oligomer Formation Propensities of Dimeric Bundle Peptides Correlate with Cell Penetration Abilities
ACS Central Science (2018) 4, 885-893 -
Implications for human odor sensing revealed from the statistics of odorant-receptor interactions
PLoS Comp. Biol. (2018) 14, e1006175 -
From Octopus to Dendrite - Semiflexible Polyelectrolyte Brush Condensates in Trivalent Counterion Solution
J. Chem. Phys. (2018) 149, 163302 -
Time-evolving genetic networks reveal a NAC troika that negatively regulates leaf senescence in Arabidopsis
Proc. Natl. Acad. Sci. USA (2018) 115, E4930-E4939 -
Signalling networks and dynamics of allosteric transitions in bacterial chaperonin GroEL: implications for iterative annealing of misfolded proteins
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. v.373, no.1749, article no.20170182. 2018 -
Energetic Costs, Precision, and Transport Efficiency of Molecular Motors
J. Phys. Chem. Lett. (2018) 9, 513-520 -
Molecular chaperones maximize the native state yield on biological times by driving substrates out of equilibrium
Proc. Natl. Acad. Sci. U. S. A. (2017) 114, E10919-E10927 -
Ultrasensitivity of water exchange kinetics to the size of metal ion
J. Am. Chem. Soc. (Communication) (2017) 139, 12334-12337 -
Physical insight into the thermodynamic uncertainty relation using Brownian motion in tilted periodic potentials
Phys. Rev. E. (2017) 96, 012156 -
Heterogeneity in kinesin function
Traffic (2017) 18, 658-671 -
Ripping RNA by Force using Gaussian Network Models
J. Phys. Chem. B (2017) vol. 121, 3515-3522 -
A Kinetic Model for the Activation of Mammalian Olfactory Receptor
J. Phys. Chem. B (2017) 121, 1304-1311 -
Heterogeneous morphology and dynamics of polyelectrolyte brush condensates in trivalent counterion solution
Macromolecules (2017) 50, 1579-1588 -
Quantifying the Heat Disspation from a Molecular Motor's Transport Properties in Nonequilibrium Steady State
J. Phys. Chem. Lett. (2017) 121, 1304-1311 -
Decoding Single Molecule Time Traces with Dynamic Disorde
PLoS Comp. Biol. (2016) 12(12), e1005286 -
Effects of dimethyl sulfoxide on surface water near phospholipid bilayers
Biophys. J. (2016) vol. 111, 2481-2491 -
How are molecular crowding and the spatial organization of a biopolymer interrelated
Soft Matter (2016) vol. 12, 9786-9796 -
Ultraslow water-mediated transmembrane interactions regulate the activation of A2A adenosine receptor
Biophysical Journal (2016) vol. 111, 1180-1191 -
Directly measuring single molecule heterogeneity using force spectroscopy
Proc. Natl. Acad. Sci. USA (2016) vol. 113, E3852-E3861 -
Contact statistics highlight distinct organizing principles of RNA and proteins
Biophys. J. (2016) vol. 110, 2320-2327 -
Confinement-induced glassy dynamics in a model for chromosome organization
Phys. Rev. Lett. (2015) vol. 115, 198102 -
Unexpected swelling of stiff DNA in a polydisperse crowded environment
J. Am. Chem. Soc. (2015) vol. 137, 10970-10978 -
Deciphering kinetic information from single molecule FRET data that show slow transitions
J. Phys. Chem. B. (2015) vol. 119, 6974–6978 -
Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover
Science (2015) vol. 347, 1485 -
Using Simulations and kinetic network models to reveal the dynamics and functions of riboswitches
Methods in Enzymology (2015) vol. 553, 235-258 -
Effects of macromolecular crowding on the collapse of biopolymers
Phys. Rev. Lett. (2015) vol. 114, 068303 -
Communication over the network of binary switches regulates the activation of A2A adenosine receptor
PLoS Comp. Biol. (2015) 11(2): e1004044. -
Programmed folding of DNA origami structures through single-molecule force control
Nat. Commun (2014) vol. 5, 5654 -
Destabilization of i-motif by submolar concentrations of a monovalent cation
J. Phys. Chem. B. (2014) vol. 118, 4753-4760. -
Evidence of disorder in biological molecules from single molecule pulling experiments
Phys. Rev. Lett.(2014) 112, 138101 -
Development and applications of Coarse Grained models for RNA
Israel J. Chem. (2014) vol. 54, 1358-1373 -
Dynamical Transition and Heterogeneous Hydration Dynamics in RNA
J. Phys. Chem. B. (2014) vol. 118, 7910-7919 -
Destabilization of i-motif by submolar concentrations of a monovalent cation
J. Phys. Chem. B. (2014) vol. 118, 4753-4760. -
Evidence of disorder in biological molecules from single molecule pulling experiments
Phys. Rev. Lett. (2014) vol. 112, 138101 -
Sequence-dependent folding landscapes of adenine riboswitch aptamers
Phys. Chem. Chem. Phys. (2014) vol. 16, 6376 -
Mapping the intramolecular signal transduction of G-protein coupled receptors
Proteins: Struct. Func. Bioinfo. (2014) vol. 82, 727-743 -
Generalized Iterative Annealing Model for the action of RNA chaperones
J. Chem. Phys. (2013) vol. 139, 121924 -
Urea-induced denaturation of preQ1-riboswitch
J. Am. Chem. Soc. (2013) vol. 135, 12112 -
Real-Time Observation of Multiple Protein-Complex Formation with Single-Molecule FRET
J. Am. Chem. Soc. (2013) vol. 135, 10254 -
Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism
Nat. Commun. (2013) vol. 4, 1705 -
Real-time single-molecule co-immunoprecipitation analyses reveal cancer-specific Ras signaling dynamics
Nat. Commun. (2013) vol. 4, 1505 -
RNA under Tension: Folding Landscapes, Kinetic Partitioning Mechanism, and Molecular Tensegrity
J. Phys. Chem. Lett. (2012) vol. 3, 3616 -
The origin of minus-end directionality and mechanochemistry of Ncd motors
PLoS Comp. Biol. (2012) vol. 8, e1002783 -
Hidden Complexity in the Isomerization Dynamics of Holliday Junctions
Nature Chem. (2012) vol.4, 907 -
Weak temporal signals can synchronize and accelerate the transition dynamics of biopolymers under tension
Proc. Natl. Acad. Sci. (2012) vol. 109, 14410 -
Multiple barriers in forced rupture of protein complexes
J. Chem. Phys. (2012) vol. 137, 055103 -
Efficient Functional Delivery of siRNA using Mesoporous Silica Nanoparticles with Ultralarge Pores
Small (2012) vol. 8, 1752 -
Force-induced Unbinding Dynamics in a Multidimensional Free Energy Landscape
Bull. Korean Chem. Soc. (2012) vol. 33, 897 -
Chain Length Determines the Folding Rates of RNA
Biophys. J. (2012) 102, L11-L13 -
A structural perspective on the dynamics of kinesin motors
Biophys. J. (2011) vol. 101, 2749 -
Link between Allosteric Signal Transduction and Functional Dynamics in a Multisubunit Enzyme: S-Adenosylhomocysteine Hydrolase
J. Am. Chem. Soc. (2011) 113, 19807-19815 -
Capturing the essence of folding and functions of biomolecules using Coarse-Grained models
Nature Communication (2011) vol. 2, 487 -
Compaction and Tensile Forces Determine the Accuracy of Folding Landscape Parameters from Single Molecule Pulling Experiments
Phys. Rev. Lett. (2011) 106, 138102 -
Theoretical Perspectives on Protein Folding
Annu. Rev. Biophys. (2010) vol. 39, 159-183 -
Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1
Science (2010) vol. 328, 760-763 -
Urea destabilizes RNA by forming stacking interaction and multiple hydrogen bonds with nucleic acid bases
J. Am. Chem. Soc. (2009) Vol. 131, 17759-17761 -
Refolding dynamics of stretched biopolymers upon force-quench
Proc. Natl. Acad. Sci. USA (2009) Vol. 106, 20288-20293 -
Metal Ion Dependence of Cooperative Collapse Transitions in RNA
J. Mol. Biol. (2009) Vol. 393, 753-764 -
Kinesin's Backsteps under Mechanical Load
Phys. Chem. Chem. Phys. (2009) vol. 11, 4899-4910 -
Ligand-induced global transition in the catalytic domain of protein kinase A
Proc. Natl. Acad. Sci. USA (2009) vol. 106, 3023-3028 -
Force dependent hopping rates of RNA hairpins can be estimated from accurate measurement of the folding landscapes
Proc. Natl. Acad. Sci. USA (2008) vol. 105, 9604-9609 -
Effects of Trimethylamine N-Oxide (TMAO) and Crowding Agents on the stability of RNA hairpins
J. Am. Chem. Soc. (2008) vol. 130. 7364-7372 -
Kinetics of loop formation in polymer chains
J. Phys. Chem. B (2008) vol. 112 6094-6106 -
Multiple probes are required to explore and control the rugged energy landscape of RNA hairpins
J. Am. Chem. Soc. (2008) vol. 130 1538-1539 -
Revealing the bifurcation in the unfolding pathways of GFP using single molecule experiments and simulations
Proc. Natl. Acad. Sci. USA (2007) vol. 104 20268-20273 -
Mechanical control of the directional stepping dynamics of the kinesin motor
Proc. Natl. Acad. Sci. (2007) vol. 104 17382-17387 -
Stretching Homopolymers
Macromolecules (2007) vol. 40 7343-7353 -
Charge density of divalent metal cations determines RNA stability
Soc. (2007) vol. 129 2676-2682 -
Internal strain regulates the nucleotide binding site of the kinesin leading head
Proc. Natl. Acad. Sci. USA (2007) vol. 104 2175-2180 -
Mechanical unfolding of RNA: From hairpins to structures with internal multiloops
Biophys. J. (2007) vol. 92 731-743 -
Dynamics of allosteric transitions in GroEL
Proc. Natl. Acad. Sci. USA (2006) vol. 103 18939-18944 -
Size, Shape, and flexibility of RNA structures
Phys. (2006) vol. 125 194905 -
Pathways and kinetic barriers in mechanical unfolding and refolding of RNA and proteins
Structure (2006) vol. 14 1633-1645 -
Forced-Unfolding and Force-Quench Refolding of RNA Hairpins
Biophys. J. (2006) vol. 90 3410-3427 -
Kinetics of interior loop formation in semiflexible chains
J. Chem. Phys. (2006) vol. 124 104905 -
Persistence Length Changes Dramatically as RNA Folds
Phys. Rev. Lett. (2005) vol. 95 268303 -
Extracting Stacking Interaction Parameters for RNA from the Data Set of Native Structures
J. Mol. Biol. (2005) vol. 347 53-69 -
Mechanical unfolding of RNA hairpins
Proc. Natl. Acad. Sci. USA (2005) vol. 102 6789-6794 -
Can energy landscape roughness of proteins and RNA be measured using mechanical unfolding experiments?
Proc. Natl. Acad. Sci. USA (2003) vol. 100 10249-10253 -
One-pot Template Synthesis and Properties of a Molecular Bowl: Dodecaaza Macrotetracycle with mu(3)-Oxo and mu(3)-Hydroxo Tricopper(II) Cores
J. Am. Chem. Soc. (1998) vol. 120, 3819-3820 -
Effects of a quantum-mechanically driven two-state gating mode on the diffusion-influenced bimolecular reactions
Phys. (1997) vol. 107 9864
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- School of Computational Sciences, Korea Institute for Advanced Study
- 85 Hoegiro Dongdaemun-gu, Seoul 02455, Republic of Korea.