People

Prof. Jejoong Yoo’s research group investigates how the sequence of biological building blocks—DNA, RNA, and amino acids—governs complex biophysical phenomena, including protein folding, sequence-specific recognition by DNA-binding proteins, self-assembly and phase separation of macromolecules, and transport through nanochannels. Biological building blocks differ by only a few atoms, and the interaction energies between them can vary by merely a few kT. Therefore, models with atomic resolution and kT-level accuracy are essential for capturing their behavior. The group’s primary goal is to develop such models by synergistically combining molecular dynamics (MD) simulation and AI methodologies. Prof. Yoo’s long-term vision is to extend MD simulations toward experimentally relevant time and length scales, enabling realistic modeling of complex cellular processes. He has authored more than 50 publications in leading international journals, including Nature Communications, Nucleic Acids Research, and Proceedings of the National Academy of Sciences.